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Clinical Microdialysis

Microdialysis is well established as a clinical research tool in neurointensive care, tissue/organ transplantations and other ICUs, where there is a need for continuous monitoring of energy and metabolic states, and other biomarkers of local chemistry in the affected organ.

Pronexus offers dedicated analytical services for clinical microdialysis samples, which require the use of more complex bioanalytical techniques and assays, e.g. UHPLC-MS/MS and UPLC-TOF for PK studies, standard HPLC methods and enzyme immunoassays, as well as, measurements of glucose, lactate, pyruvate, glycerol and urea by CMA 600 Microdialysis Analyser used for bed-site microdialysis monitoring.